7-羰基醋酸去氢表雄酮的合成研究

来源 :中国化学会第九届全国有机化学学术会议 | 被引量 : 0次 | 上传用户：xiongying1207

【摘要】

：

7-羰基醋酸去氢表雄酮(7-keto-dehydroepiandrosterone acetate)简写7-Keto DHEAAC,分子式C21H28O4,是去氢表雄酮(DHEA)的类似物,也是一种有显著生理活性的甾体药物[1],既能抗衰老、增强机体免疫力、预防糖尿病,还能改善脑功能、增强记忆力、预防老年痴呆、刺激肝脏活性酶,特别是热酶的代谢,有减少心脏病发病率、减少脂肪、减肥,维持正常体质指数,

【作者】

：

田光辉赖普辉闫竹梅翟振琪刘存芳

【机构】

：

陕西理工学院化学与环境科学学院陕西汉中,723001 城固县振华生物科技有限责任公司陕西城固,

【出处】

：

中国化学会第九届全国有机化学学术会议

【发表日期】

：

2015年7期

【关键词】

：

7-酮基醋酸去氢表雄酮合成结构表征非激素类药物

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Synthesis and Relational Chemicobiological Study of Novel Antimicrobial Naphthalimide-based Imidazol

A series of Schiff base-appended naphthalimide-based imidazoles as a novel type of potential antimicrobial agents were synthesized and characterized by NMR,IR,MS and HRMS spectroscopy.

会议

Synthesis and Evaluation of Magnolol Derivatives Containing Aspirin as Potent Anti-inflammatory Agen

Aspirin[1-2] is well known as a nonsteroidal anti-inflammatory drug possessing a free carboxylic acid group.

会议

BODIPY类荧光染料的合成及光泵激光性质研究

BODIPY 类染料作为可调谐激光和光电器件材料的活性介质,日益得到人们的关注和重视.该类染料以其光化学稳定性好、激光转换效率高、较大的激光发射和可调范围、溶解度好、激发态吸收截面小、三重态驰豫效率小等优点极大提升了光响应能力.

会议

Synthesis and Antimicrobial Evaluation of Novel Quinolone Imidazoles and Their Interactions with MRS

Fluoroquinolones are an important kind of synthetic antibacterial agents.However,these drugs were extensively developed for treatment of infections caused by Gram-negative bacteria,only had limited ac

会议

Advances in the novel borate esters containing heterocycle as environmental friendly lubricant addit

Under the background of the global energy shortage and environmental protection as well as the rapid development of China economy,it is a great challenge to achieve a green,fast and healthy "GDP".

会议

3-(蒽醌-2-乙烯基)-N-乙基咔的合成与BSA的相互作用

利用N-乙基咔唑-3-甲醛和2-氨基蒽醌合成具分子内电荷转移性质的化合物3-(蒽醌-2-乙烯基)-N-乙基咔唑(合成步骤见图1).化合物结构经核磁表征:1H NMR(300MHz,CDCl3),δ:6.858(2H,-CH=CH-);8.6～7.26(14H,咔唑和蒽醌);4.4(2H,-CH2);1.41～1.38(3H,-CH3).

会议

Design,Synthesis,Antiviral Activity and Mechanism of Action of Phenanthrene-Containing N-Heterocycli

Phenanthroindolizidine alkaloid antofine and its analogues have excellent antiviral activity against tobacco mosaic virus(TMV).

会议

Design and Bioevaluation of Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors for Herbicide Disco

4-Hydroxyphenylpyruvate dioxygenase(HPPD),converting 4-hydroxyphenyl pyruvate acid to homogentisate,is very important for the biosynthesis of the plastoquinone and tocopherol,which are essential cofac

会议

Design,Synthesis and Structure-activity Relationships of 3-O-β-chacotriosyl Ursolic Acid Derivatives

H5N1 avian influenza A virus is the cause of significant morbidity among humans,posing a serious threat to public health due to its transmission from animals to human being.

会议

甾体药物中间体6-亚甲基单酯“一锅法”合成及结构表征

6-亚甲基单酯是合成一些终端原料药如甲地孕酮、安宫黄体酮、可的松醋酸酯、己酸孕酮等甾体激素类药物的关键中间体[1],化学名称：17α-乙酰氧基-6-亚甲基孕甾-4-烯-3,20-二酮(17α-Acetyloxy-6-methyleneprogn-4-ene-3,20-dione)。

会议

一锅法合成6-亚甲基单酯结构表征

7-羰基醋酸去氢表雄酮的合成研究

与本文相关的学术论文