【摘 要】
：
NMDA receptor (NMDA-R) antagonists elicit psychotic symptoms in human and schizophreniarelevant signs in rodents, including a strong increase in gamma activity in different cortical areas.NMDA-Rs are
【机 构】
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Harvard Medical School USA
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NMDA receptor (NMDA-R) antagonists elicit psychotic symptoms in human and schizophreniarelevant signs in rodents, including a strong increase in gamma activity in different cortical areas.NMDA-Rs are composed of several subunits and the major differences in the distribution and dynamical properties of NMDA-Rs containing the NR2A and NR2B subunits indicate that they may play different roles in cortical network activity, and that hypofunction of these receptors may differently affect gamma activity, critical for a number of cognitive functions.The goal of the present study was to test this hypothesis.
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