Objective: Rapid growth of tumor cells needs to consume large amounts of oxygen and glucose, due to lack of blood supply within the tumor, cells live in an environment that lack of oxygen and nutrient
Background: The combination of the highly selective c-Met inhibitor tepotinib (MSC2156119J) + gefitinib was shown to be well tolerated and have antitumor activity possibly associated with c-Met-positi
Objective: Recent studies indicate that autophagy is adouble-edged sword in tumor genesis and plays an important role in theresistance of cancer cells to chemotherapy.We hypothesize that autophagy pro
Objective: Small cell lung cancer (SCLC) is a refractory subtype of lung cancer characterized by limited drug responses, aggressive metastasis and relapse at relatively earlystage when compared to non
Objective: To observe the efficacy and safety of pulsatile administration of high-dose gefitinib or erlotinib for advanced non-small cell lung cancer patients with secondary drug resistanceto standard
目的: Malignant pleuraleffusion (MPE) is mainly caused by metastatic pleuralcancer and defines malignant tumors with apoor prognosis.To achieve sufficient control of MPE and to minimize invasive interve
Objective: Along with the research progress of lung cancer-related driver genes, echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinas (EML4-ALK) positive non-small cell lung canc
目的: Twist1 over expression has been reported to correspond with poorsurvival in non-small cell lung cancer (NSCLC), but the underlining mechanismis not clear.The objective of the present study was to