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5. PAMAM dendrimers-mediated specific targeting and intracellular apoptosis with aptamer and Bcl-2 conv

PAMAM dendrimers-mediated specific targeting and intracellular apoptosis with aptamer and Bcl-2 conv

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：tina_lh

【摘 要】

：

A short Nur77-derived peptide NuBCP-9 was reported to exhibit the remarkable apoptotic capability to Bcl-2-positive cancer cells in our previous work[1].However,it was not accessible to cell interior

【作 者】

：

Jingjing Xie Xiaohui Chen Pengjin Ge Fengyu Huang Xiaokun Zhang 

【机 构】

：

School of Pharmaceutical Sciences,Xiamen University,Xiang'an South Road,Xiamen,Fujian 361102,China

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

anticancer peptide PAMAM dendrimers cell targeting cell penetration cell apoptos 

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　　A short Nur77-derived peptide NuBCP-9 was reported to exhibit the remarkable apoptotic capability to Bcl-2-positive cancer cells in our previous work[1].However,it was not accessible to cell interior to exert the anticancer function until taken by the cell-penetrating peptide (CPP) or nano carriers.

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