A general accounting of progress, concerns, and changes over the past half century for principally the oyster culture fishery in the US is provided for the three major coastal regions; Atlantic Coast, Gulf of Mexico Coast, and Pacific Coast.Although other species of oysters are being grown especially on the Atlantic and Pacific Coast, the principle species is Crassostrea virginica for the Atlantic and Gulf of Mexico coastal regions, and Crassostrea gigas for the Pacific region.Each region has shown to be unique in its own specific requirements and needs to maintain a healthy oyster fishery.There are problems too, as shown as one example of major oyster growing areas in the past as the Chesapeake Bay/Delaware Bay and other bays along the Atlantic Coast having suffered greatly from disease and in part pollution concerns.Another is the Katrina Hurricane in 2005 and more recently the impact of the British Petroleum off-shore oil breach which essentially caused major disastrous setbacks and loss of an industry as in the State of Louisiana and adjacent states in the Gulf of Mexico.