ESCRTs cooperate with an autophagy receptor to drive vacuolar targeting of soluble cargos

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:chenshuae9o
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Autophagy transports cytosolic materials into lysosomes/vacuoles either in bulk or selectively.The best understood autophagic mechanism is macroautophagy, which features the double-membrane-bound transport vesicle called autophagosome and requires the core autophagy-related (Atg) proteins.
其他文献
  Rab proteins are key regulators of cellular trafficking.Rab5 and Rab7 are endocytic Rab proteins functioning in modules to regulate vesicle trafficking from
会议
  ZNF32 is a recently identified zinc finger protein and its functions remain largely unknown.Autophagy has been shown to affect cell proliferation and surviv
会议
  Autophagy is an intracellular process of uptaking and degrading cytoplasmic organelles and other materials.It is a conserved degradation pathway among all e
会议
  Introduction.Mechanosensory osteocytes (OYs) are the most abundant and long-lived (up to decades) cells entombed in bone.The longevity of osteocytes is achi
会议
  Autophagy is a dynamic process accomplished by the generation and maturation of autophagosomes.Isolation of autophagosomes and subsequent compositional anal
会议
  Dyslipidemia, a principal symptom of the metabolic syndrome and diabetes mellitus, exposes the heart to elevated circulating levels of fatty acid (FA).
会议
  Autophagy, evoked by diverse stresses including myocardial ischemia/reperfusion (I/R), profoundly affects the development of heart failure.
会议
  Autophagy is an evolutionarily conserved lysosome-dependent degradative process that intracellular material is degraded to fuel starving cells and eliminate
会议
  Oogenesis is essential for female gamete production in mammals.The total number of ovarian follicles is determined early in life and production of ovarian o
会议
  Hyperammonemia is frequently seen in liver diseases where it can lead to severe brain damage or death,as well as in tumor microenvironments.Ammonia was rece
会议