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A near infrared (NIR) triggered drug delivery platform based on the chitosan modified chemically reduced graphene oxide (CRGO) incorporated into a thermosensitivenanogel (TGN) was developed.TGN exhibited a NIR-induced thermal effect similar to that of CRGO,reversible thermo-responsive characteristics at 37-42℃ and high doxorubicin hydrochloride (DOX) loading capacity (48 wt%).