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A facile fluorescent sensor based on molecularly imprinted polymer coated on carbon quantum dots(CQDs@MIPs)for highly sensitive and selective tobramycin sulfate(TS)detection.The CQDs@MIPs were prepared using a reverse micro emulsion method process with 3-aminopropylethoxysilane as a functional monomer,tetraethoxysilane as a cross-linker and tobramycin sulfate as a template molecule.