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NOD样受(NLR)体为近年来发现的一类位于细胞质内的模式识别受体，能够识别进入胞内的病原分子从而引起免疫应答，是机体天然免疫系统的重要组成部分.目前已经鉴定出的NLR家族至少包含22种人类成员和34种鼠源成员.NLRC4是NLR中的一员，主要识别细菌的鞭毛蛋白和Ⅲ型分泌系统的成分.
NLRC4的自抑制分子机制
【摘 要】
：
NOD样受(NLR)体为近年来发现的一类位于细胞质内的模式识别受体，能够识别进入胞内的病原分子从而引起免疫应答，是机体天然免疫系统的重要组成部分.目前已经鉴定出的NLR家族
【机 构】
：
清华大学生命科学学院,北京100084
【出 处】
：
2013年第四届全国“跨学科蛋白质研究”学术讨论会
【发表日期】
：
2013年10期
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