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Objective:Traditional Chinese Medicine Constitution (TCMC) theory is widely applied in the practice of medical treatment for thousand years in China, which is identified as the treasure of Chinese civilization.TCMC determined the susceptibility to certain disease and therapy effect, which can be divided into normal constitution and unbalanced ones.This study aims at investigating the distribution and the characteristic of TCMCs in adult Chinese resident in Changsha and the effects on susceptibility and therapy effect of hypertension.