Circulatory system is very important for the transportation of nutrient, metabolic waste and signaling molecules in human body.Blood vessels and lymphatic vessels take the main job for the transport, and they have the tubular structures, which consist of different cells and extracellular matrix.Therefore, the in vitro modeling of microvessels is an essential work in the study of drug screening, tissue/organ-on-a-chip and regenerative medicine.General strategies are unsatisfactory for their cytotoxicity or complex procedures.