Ali-trans retinoid acid pre-treatment reduced myocardial ischemia/reperfusion-induced cell death in

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户:zhudebaotogogo
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Background Myocardial ischemia/reperfusion (I/R) injury interferes with the beneficial effects of blood flow restoration to the ischemic myocardium.Oxidative stress-elicited apoptosis has been reported to contribute to I/R injury.All-trans retinoid acid (ATRA),a vitamin A derivative,has anti-oxidative activity,and anti-apoptotic effects as previously reported.However,the activity of ATRA with respect to myocardial I/R injury is uncertain.
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