【摘 要】
：
腺点金丝桃(Hypericum scabrum L.)为藤黄科(Guttiferae)金丝桃属多年生草本植物.腺点金丝桃是我国新疆特有种,仅分布在天山、阿尔泰山、塔尔巴哈台山前山至中山地区1.该属植
【机 构】
：
中国医学科学院&北京协和医学院药物研究所,天然药物活性物质与功能国家重点实验室,北京,100050
【出 处】
：
中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
腺点金丝桃(Hypericum scabrum L.)为藤黄科(Guttiferae)金丝桃属多年生草本植物.腺点金丝桃是我国新疆特有种,仅分布在天山、阿尔泰山、塔尔巴哈台山前山至中山地区1.该属植物富含间苯三酚类化合物,现代药理实验证明间苯三酚类化合物对于治疗轻中度抑郁症具有效果好、副作用低的特点2.我们对腺点金丝桃的95％乙醇提取物的乙酸乙酯萃取部位经过大孔树脂处理,分离得到了4个间苯三酚类化合物和2个口山酮类化合物.分别鉴定为:furo-adhyperforin (1)、1-(2-methy-l-oxopropyl)-2,12-di-oxo-3,10-bis(3-methyl-2-butenyl)-6-hydroxy-11-methyl-11-(4-methyl-3-pentenyl)-5-oxatricyclo[6.3.1.04,8]-3-dodecene3 (2 和 3)、 oxepa-hyperforin (4)、大黄素(5)和1,3-二羟基-6-甲氧基口山酮(6),其中,化合物6为新的天然产物.
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