【摘 要】
：
Objective: Beta-amyloid (Aβ) deposition and associated neuroinflammation are considered as important factors leading to cognitive deficits in Alzheimers disease (AD).Icariside Ⅱ (ICS Ⅱ) is one of the
【机 构】
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Department of Pharmacology and Key Laboratory of Basic Pharmacology of Ministry of Education,Zunyi M
【出 处】
：
第六届中国药理学会补益药药理专业委员会学术研讨会
论文部分内容阅读
Objective: Beta-amyloid (Aβ) deposition and associated neuroinflammation are considered as important factors leading to cognitive deficits in Alzheimers disease (AD).Icariside Ⅱ (ICS Ⅱ) is one of the active flavonoid compounds of Epimedium brevicornum, a Chinese herb extensively used for the treatment of dementia.In this study, we attempted to determine the effects of ICS Ⅱ on behavioral deficits, Aβ levels, neuroinflammatory responses induced by intracerebroventricular injection of Aβ25-35 in rats.
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