胆囊结石临床症状进展的危险因素研究

来源 :中华医学会第十七届全国外科学学术会议 | 被引量 : 0次 | 上传用户:xuxu517
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目的 研究胆囊结石确诊后由无临床症状向有临床症状发展的危险因素,探讨胆囊结石的临床进程,为预防由于胆囊结石诱发的严重并发症及规范胆囊切除手术指征提供依据.方法 收集2008-2010年北京协和医院基本外科胆囊结石切除术患者共1000例.以年龄和性别为配对因素匹配,分别纳入无症状胆囊结石组,胆绞痛组,胆囊炎组.终点为临床症状出现时间.比较各组患者间家族史及相关病史、胆囊局部情况、结石特征、体重指数、以及血清生化学指标等差异.采用单因素分析和多因素Cox回归方法分析相关危险因素.
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