【摘 要】
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Background,Motivation and Objective The broadband inertial cavitation signals from microbubbles(MBs) have been used for detecting and monitoring drug release.Rupturing MBs in general requires a signif
【机 构】
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Center for Ultrasound Molecular Imaging and Therapeutics,University of Pittsburgh School of Medicine
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Background,Motivation and Objective The broadband inertial cavitation signals from microbubbles(MBs) have been used for detecting and monitoring drug release.Rupturing MBs in general requires a significantly large negative peak pressure and long pulses,which both raise safety concerns and limit the spatial resolution of cavitation images.Phase transition droplets have been proposed as promising contrast agents for ultrasound(US) and photoacoustic imaging and drug delivery vehicles.In our study of laser-triggered droplets,it was found that vaporized droplets as form of bubbles cavitate and rupture in response to a relatively short acoustic pulse that allows for imaging inertial cavitation at high spatial resolution.In this study,the cavitation imaging of the laser-triggered droplets with high spatial resolution is demonstrated.
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