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为了探讨≥30岁伴乳头溢液乳腺癌患者的临床诊断方法,回顾性研究163例(164个病灶)≥30岁单纯乳头溢液、乳头溢液合并肿块、乳头溢液合并局限性增厚乳腺癌患者的临床资料,分析患者乳腺X射线(MG)、超声(US)、乳管内视镜(MD)和MG联合US、MG联合MD的检查结果,进行统计学分析。单纯性乳头溢液乳腺癌MG、US和MD的阳性率分别是32.9%、16.5%和69.6%,合并肿块乳腺癌的阳性率分别为48.2%、42.9%和83.9%,合并局限性增厚乳腺癌的阳性率分别为82.8%、37.9%和79.3%。MG联合US在本研究各亚组中的阳性率和MG单独检查相比有提高,但差异无统计学意义(P>0.05),MG联合MD在合并腺体局限性增厚乳腺癌组中的阳性率和MG单独检查相比有提高,差异无统计学意义(P=0.23),但在其他两个亚组中差异有统计学意义,P=0.000。初步研究结果提示,单纯乳头溢液或乳头溢液合并肿块的患者诊断时行MG联合MD检查,可补充US检查,而乳头溢液合并局限性增厚患者行MG检查,可补充MD和US检查。
In order to investigate the clinical diagnosis of ≥30-year-old patients with nipple discharge breast cancer, 163 cases (164 lesions) of simple nipple discharge ≥30 years, nipple discharge with mass, nipple discharge with limited thickened breast The clinical data of patients with cancer were analyzed. The results of mammography, sonography, endoscopy (MD) and MG combined with US and MG were analyzed and statistically analyzed. The positive rates of MG, US and MD in patients with simple nipple discharge were 32.9%, 16.5% and 69.6%, respectively. The positive rates of combined mass breast cancer were 48.2%, 42.9% and 83.9% respectively, The positive rates of cancer were 82.8%, 37.9% and 79.3% respectively. The positive rate of MG combined with US in each subgroup of this study was increased compared with that of MG alone, but the difference was not statistically significant (P> 0.05). The combination of MG and MD in the group of breast gland hyperplasia There was no significant difference between the two groups (P = 0.23), but there was a significant difference between the other two subgroups (P = 0.000). Preliminary findings suggest that patients with simple papillary discharge or nipple discharge with mass in the diagnosis of MG combined with MD examination can be added to the US test, and nipple discharge with limited thickening MG patients with MG, can be added to check the MD and US .