Objective Elevation of intraocular cAMP facilitates neuronal survival in CNS.Papaverine is an panphosphodiesterase inhibitor which could inhibit the degradation of intracellular cAMP.The aim of this s
Purpose The aim of this investigation was to investigate whether a PVCL-PVA-PEG nanomicelle formulation could overcome some of the obstacles presented by topical ophthalmic curcumin formulations and p
Purpose To s whether high pressure directly induced mtDNA damage and mutations of RGCs and the subsequent mitochondrial dysfunction.Methods The primarily cultured RGCs were exposed to hydrostatic pres
Purpose To investigate the molecular changes related to the dedifferentiation and proliferation of Müller cells in response to neurotoxic injury in the retina.Methods The neurotoxic injury was induced
Purpose To investigate the altering expression profiles of efflux transporters at the inner blood-retinal barrier(BRB)during the development of early diabetic retinopathy(DR)and/or aging in mice.Metho