Self-reactive T cells participate in inflamm-aging due to compromised thymic negative selection, but

来源 :2014 International Conference on Aging and Disease(2014年第一届衰 | 被引量 : 0次 | 上传用户:zeroorhero
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  Age-related chronic persistent low-grade pro-inflammatory state, termed inflamm-aging, is attributed to senescence-associated secretory phenotype (SASP) and persistent activation of immune cells.The persistent activation of immune cells was reported to be mainly attributed to long-term viral infections, such as cytomegalovirus (CMV), etc.
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