PRMT5 enhances the generation of induced pluripotent stemcells(iPSCs) from dairy goat embryonic fibr

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户:lohansun
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
PRMT5, protein arginine methyltransferase 5 is thought to play a role in epigenetic reprogrammingin mouse germ cells.However, there were little information on the expressionprofile of PRMT5 and their effects on the generation of livestock induced pluripotent stemcells(iPSCs) from somatic cells.
其他文献
It is well known that cell surface glycans or glycocalyx play important roles in sperm motility, maturation and fertilization.A comprehensive profile of the sperm surface glycans willgreatly facilitat
Arsenic (ATO) is highly effective for treating acute promyelocytic leukemia (APL),it may also be potentially effective for many other tumors.To explore this potential, it isnecessary to understand the
Candida albicans is an opportunistic pathogen, often causing both mucosal and systemicinfections in immune-compromised patients.The C.albicans can switch heritably and athigh frequency between several
会议
The concept of minimum genome factories (MGFs) has been proposed, which can bedefined as recombinant strains whose metabolism has been streamlined to the optimalminimal subset in order to maximize pro
Introduction Anterior gradient 2 (AGR2), a novel tumor target protein associated with metastatic progressionof breast cancer as well as other malignant cancers.Insulin-like growth factor-1 (IGF-1) is
随着越来越多具有功能lncRNA被发现,IncRNA新的作用机制也逐步被揭示出来.然而,大多数lncRNA对研究中通常检测的细胞生物学效应的影响不明显,使lncRNA功能研究受到了制约.我们希望通过检测表达受到lncRNA影响的基因,进而推断出lncRNA相关功能.为此,我们将多重PCR的方法应用到了lncRNA功能研究中.多重PCR是在同一PCR反应体系里可以同时扩增多个基因片段的PCR反应.目
The IQ-domain GTPase-activating protein 1 (IQGAP1) is a multifunctional scaffold protein,which interacts with diverse proteins to regulate cell adhesion and cell migration.And theabnormal expression o
Caenorhabditis elegans live in the soil, a complex environment.They has developed astmcture-simple but fully functional system of neurons, which make them become amodel organism for studying the devel
Objective: To investigates the meaning of these genes expression character and thephysiological significance of HIF-1α and HIF-1α for microtus oeconomus to survive at highaltitude environment.Methods:
Homologous recombination (HR) is a strategy for genetic correction.The efficiency of HRcan be increased by creating a targeted double-strand break (DSB) via zinc-finger nucleases(ZFNs) and/or by intro