Effect of coexisting polymorphisms of CYP2C19 and P2Y12 on pharmacodynamics and adverse clinical eve

来源 :2013中国心脏大会(CHC) | 被引量 : 0次 | 上传用户:robert198121
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Background CYP2C19 G681A single polymorphism had been proved to effect on clopidogrel responsiveness.However, the effect of coexisting polymorphisms of the genes has not yet been reported in Chinese population.The present study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel phannacodynamics and adverse clinical events in Chinese patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention (PCI).
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