【摘 要】
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To date,the creative design of polymeric nanocarriers possessing thermo responsive behavior attracts substantial interest in the fabrication of smart materials for drug delivery systems.In this aspect
【机 构】
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BK21 PLUS Center for Advanced Chemical Technology,Department of Polymer Science and Engineering,Pusa
【出 处】
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The Third Symposium on Innovative Polymers for Controlled De
论文部分内容阅读
To date,the creative design of polymeric nanocarriers possessing thermo responsive behavior attracts substantial interest in the fabrication of smart materials for drug delivery systems.In this aspect,we have focused on a new multi-arm hyperbranched copolymer combining a temperature responsive poly(N-isopmpylacrylamide) (p(NIPAM)) with a biocompatible hyperbranched polyglycidol (HBP) [1].A series of novel HBP-b-[p(NIPAM)n]6 (n =15,25,35,45) chimeric copolymers were successfully synthesized by combining ring-opening multi branching polymerization of glycidol,followed by nitroxide-mediated polymerization by utilizing HBP-TEMPO as macroinitiator.
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