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5. Ubiquitination-deficient mutations in Piwi gene Hiwi leads to human asthenozoospermia/azoospermia

Ubiquitination-deficient mutations in Piwi gene Hiwi leads to human asthenozoospermia/azoospermia

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：binwuwu

【摘 要】

：

Genetic studies in various animal models indicate that Piwi genes are crucial to animal germline development.However, whether mutation in Piwi contributes to human infertility remains largely unexplor

【作 者】

：

Lan-Tao Gou Jun-Yan Kang Peng Dai Xin Wang Man Zhang Yi Lu Jinsong Li Hui-Juan Shi Mo-Fang Liu 

【机 构】

：

Center for RNA Research, State Key Laboratory of Molecular Biology-University of Chinese Academy of

【出 处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

HIWI MIWI ubiquitination spermiogenesis asthenozoospermia azzospermia 

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　　Genetic studies in various animal models indicate that Piwi genes are crucial to animal germline development.However, whether mutation in Piwi contributes to human infertility remains largely unexplored.

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