The bifunctional Pt/ZSM-22 catalysts with 0.5% platinum were prepared by means of the wetness impregnation technique using three platinum precursors: platinum nitrate (PtNO3), hexachloroplatinic acid (H2PtCl6) , tetraamminplatinum chloride (Pt(NH3)4Cl2). The texture, crystal phase and surface metal/acidity functions were characterized by the techniques such as N2-sorption, XRD, SEM, ICP, FT-IR, CO-chemisorption and NH3-TPD. It was shown that the catalyst prepared by hexachloroplatinic acid with the highest platinum dispersion and nPt/nA value exhibited stronger metal–support interaction and higher metal dispersion than those prepared by platinum nitrate and tetraamminplatinum chloride. The intimate metal–acid interaction and the enhanced (de)hydrogenating capability of this catalyst led to the highest catalytic activity and isomerization selectivity in n-hexadecane hydroconversion.