【摘 要】
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Objective To investigate the long noncoding RNA (lncRNA) NONHSAT112178 as a biomarker for coronary artery disease (CAD) in peripheral blood monocyte cells (PBMC).Method RT-qPCR was performed to valida
【机 构】
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Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R.Chi
【出 处】
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第17届中国南方国际心血管病学术会议
论文部分内容阅读
Objective To investigate the long noncoding RNA (lncRNA) NONHSAT112178 as a biomarker for coronary artery disease (CAD) in peripheral blood monocyte cells (PBMC).Method RT-qPCR was performed to validate the microarray results, ROC curve was applied to study the potential of NONHSAT112178 as a biomarker.Diagnostic models from NONHSAT112178 alone or combination of risk factors were constructed by Fisher criteria.The function of NONHSAT112178 was confirmed in THP-1 cell line by siRNA.
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