Endocrine-disrupting chemicals (EDCs) are a large group of environmental toxicants that pose serious risks to public health;however,methods for the effective degradation of EDCs are lacking.In this study,we report a new method for the complete degradation of EDCs by a biodegradation-active composite of biogenic manganese oxides and engineered Escherichia coli cells surface-expressing the multicopper oxidase CotA.The cotA gene from a Mn2+-oxidizing bacterium was expressed in Escherichia coli,enabling the display of catalytic CotA on the surface of the cells.