Ischemic preconditioning protects against liver ischemia/reperfusion injury via heme oxygenase-1-med

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:tataba56
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Background: Ischemic preconditioning (IPC) exerts a protective effect in hepatic ischemia/reperfusion (I/R) injury.The exact mechanism of IPC action remains largely unknown.Recent studies suggest that autophagy plays an important role in protecting againstI/R injury.However, the role of autophagy in IPC-afforded protection and its regulatory mechanisms in liver I/R injury remain poorly understood.This study was designed to determine whether IPC could protect against liver I/R injury via heme oxygenase-1 (HO-1)-mediated autophagy.
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