PINK1 and Parkin crosstalk synucleinopathies by mitophagy

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：superlhl2010

【摘要】

：

PINK1 is a mitochondrial serine/threonine kinase,which protects mitochondria from cellular stress and regulates neuronal differentiation.

【作者】

：

Jian-She Wei Ping Li Yi Wang Jian-Nan Wu Nan-Nan Wei Zhi-Quan Zhao Wen-Jin Xia Cong-Cong Li

【机构】

：

Institute for Brain Science Research,Laboratory of Brain Function and Molecular Neurodegeneration,Ka

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

PINK1 Parkin Mitophagy Fission Fussion Synucleinopathies

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　PINK1 is a mitochondrial serine/threonine kinase,which protects mitochondria from cellular stress and regulates neuronal differentiation.

其他文献

Augmentation of necroptosis dependent enzymatic activity induces spatial short term memory impairmen

Necroptosis is a novel cell death pathway and Glutamate-ammonia ligase(GLUL)and glutamate dehydrogenase-1(GLUD1)enzymes have vital functions in this type of cell death.

会议

necroptosishippocampusspatial memory

Activity and activity pattern in human visual cortex could reveal the contents of visual awareness

会议

visual awarenessbistable perceptionfMRIMVPAcategory information

Inhibitory interneuron subtypes differentially regulate beta and gamma band oscillatory activity in

Neuronal population activity in the intact brain often exhibits different rhythmic patterns of distinct frequency ranges(0.01–120 Hz).

会议

beta gamma oscillationsinhibitory interneuronlocal field potentialsingle unit

Increased association of the adenosine A2A receptor and dopamine D2 receptor heterodimers after rand

Striatal adenosine A2A receptors(A2ARs)modulate striatal synaptic plasticity and instrumental learning,possibly by functional interactions with the dopamine D2 receptor(D2R)and metabotropic glutamate

会议

A2A receptorD2 receptormetabotropic glutamate receptor 5receptor-receptor het

What can be learned from deep brain recordings in human?

The surgery of deep brain stimulation has provided a unique opportunity to record directly from the deep structures of human brain.

会议

Neural biomarkerslocalizationsubthalamic nucleuslocal field potentialsdeep b

Amyloid precursor protein regulates GABAergic signaling in prefrontal cortex in mice

会议

Alzheimer’s diseaseamyloid precursor proteinprefrontal cortexGABAergic transm

An experimental study of the effect of cAMP/p-CREB signal pathway on circadian rhythm of AD

Alzheimers disease is a progressive neurodegenerative disorder in the presenium and geratic period,which is characterized by impaired cognition,learning,memory.

会议

Alzheimer’s diseasecircadian rhythmcAMP/p-CREB signal pathway

Dihydromyricetin reduces α-synuclein aggregation via autophagy pathway

Progressive accumulation of α-synuclein is a key step to pathological development of Parkinsons disease and dementia with Lewy bodies.

会议

alpha-synucleinParkinson’s diseaseProtein aggregationautophagy

Prognostic power of the combination of MRI and structural network for the discrimination of conversi

会议

mild cognitive impairmentMRIstructural networkclassification

The Influence of Substantia Nigra Neurons and Akt through Acupuncture of Chorea-tremble Controlled A

Objective To study the protective effect of acupuncture of Chorea-tremble controlled area combined with madopar on the dopaminergic neurons in Parkinsons disease(PD)and the possible mechanism of treat

会议

Parkinson’s disease1-methyl-4-phenyl-1236-tetrahydropyridineChorea-tremble

PINK1 and Parkin crosstalk synucleinopathies by mitophagy

与本文相关的学术论文