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5. Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome

Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：tp13140

【摘 要】

：

Objects: To analyze the impact of WAS gene mutation on the number and function of follicular helper T cells in children with Wiskott-Aldrich syndrome (WAS) and WAS KO mice.Methods:Fresh blood samples

【作 者】

：

Xuan Zhang Rongxin Dai Hongqiang Du Guangjin Luo Junfeng Wu Wenxia Song Linlin Niu Yunfei An Zhiyong Zhang Yuan Ding Xiaodong Zhao 

【机 构】

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Division of Immunology,Children's Hospital of Chongqing Medical University,Chongqing,China

【出 处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

T follicular helper cell Wiskott-Aldrich syndrome ICOS BCL6 memory response 

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　　Objects: To analyze the impact of WAS gene mutation on the number and function of follicular helper T cells in children with Wiskott-Aldrich syndrome (WAS) and WAS KO mice.Methods:Fresh blood samples of 35 WAS patients and 35 age-matched healthy children (HC) were collected.

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