【摘 要】
：
We showed that healthy older adults and Alzheimer Disease (AD) patients maintain intact haptic and visual repetition priming.Despite the intact priming, AD patients explicit recognition was highly imp
【机 构】
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Department of Basic Psychology Ⅱ Universidad Nacional de Educación a Distancia Spain
【出 处】
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BIT`s 3rd Annual World Congress of NeuroTalk-2012(2012第三届国际神
论文部分内容阅读
We showed that healthy older adults and Alzheimer Disease (AD) patients maintain intact haptic and visual repetition priming.Despite the intact priming, AD patients explicit recognition was highly impaired compared to healthy adults.Further studies from our laboratory also showed that priming (visual, auditory and haptic) for stimuli presented to the same (within-modal) or to different modalities (crossmodal) at study and test is preserved in the old age.The question is whether the neural correlates of priming are preserved in older adults.Electroencephalographic (EEG) studies conducted to investigate the neural markers of priming for visual words and objects explored by touch exhibit age-related changes in brain activity despite of the similar behavioral performance of young and older adults.Electrophysiological and brain imaging studies suggest that older adults compensate their lower level of parietooccipital functioning by recruiting anterior frontal sites.Moreover, an event-related fMRI study conducted to investigate age-related changes in brain activity in young and older adults while performing a visual conceptual implicit memory task suggest that the two groups showed repetition related activation reduction in several brain regions but reductions were smaller in the older group.These results suggest that with aging important changes occur in the neural architecture that mediates repetition priming.The speared behavioral perceptual and conceptual priming observed in older adults is achieved enhancing brain activity with stimulus repetition.The relationships between brain function and behavior observed in young adults are altered in older adults.
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