Effects of neuregulin-1β on growth-associated protein 43 expression in dorsal root ganglion neurons

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Neuregulin-lβ (NRG-1β) is a growth factor with potent neuroprotective capacity.Growth-associated protein 43 (GAP-43) is expressed in dorsal root ganglion (DRG)neurons and an indicator of neuronal survival in vitro.The purpose of present study is to evaluate the effects of NRG-1β on GAP-43 expression in DRG neurons with excitotoxicity induced by glutamate (Glu) in vitro.
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