Objective:To evaluate the efficacy of autologous platelet rich-plasma rPRP、combined with erbium fractional laser for facial acne or acne scar Methods:PRP combined with erbium fractional laser was used for treatment of 22 patients,including 1 6 patients who were suffered from facial acne scar,while 6 patients were acne scar concomitant acne Fortv milliliters whole blood of each patient was collected. undergoing differential centrifugation PRP was harvested After using erbiurn fractional laser,we coated PRP on whole face of every patient Digital photos were taken before and after the treatment for dermatologists and the patients rate the efficacy 1n a 5-points scales Results:The erythema was moderate or mild while 1ts total duration was less than 3 days;after receiving the treatment for three times.91 7%of the patients have 1mprovement of over 50%and 91%of the patients are satisfied.the 1nflammation of ance was extincted Conclusion:PRP combined with erbiurn fractional laser 1s an effective and saftr way to treat acne scar or acne with minimized side effects,simultaneously enhanced recovery of laser-damaged skin