• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Protein kinase TTK promotes proliferation,migration and mediates epithelial-mesenchymal transition i

Protein kinase TTK promotes proliferation,migration and mediates epithelial-mesenchymal transition i

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户：liuxuedong0628
【摘 要】
：
Objective Bladder cancer is the second most commonly diagnosed genitourinary neoplasm,with approximately 360,000 new cases diagnosed worldwide and 145,000 deaths each year.
【作 者】
：
Feiran Chen Jun Du Guowei Feng Xin Yao 
【机 构】
：
Tianjin Medical University Cancer Institute and Hospital
【出 处】
：
2019中国肿瘤学大会
【发表日期】
：
2019年7期
【关键词】
：
Bladder cancer TTK Proliferation Migration EMT 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Objective Bladder cancer is the second most commonly diagnosed genitourinary neoplasm,with approximately 360,000 new cases diagnosed worldwide and 145,000 deaths each year.
其他文献
高通量测序筛选骨肉瘤发生和肺转移相关的lncRNA-miRNAmRNA调控网络
目的 骨肉瘤(OS)是最常见的小儿恶性骨肿瘤，肺转移的发生通常导致快速进展且致命的后果。我们拟通过分组系统分析在原发性骨肉瘤患者组和肺转移骨肉瘤患者组中的microRNA(miRNA)，长链非编码RNA(lncRNA)和mRNA 的差异表达情况旨在揭示调控骨肉瘤发生和肺转移的调控机制。
会议
miRNAlncRNAmRNA骨肉瘤转移
N-Myc-interacting protein negatively regulates epithelialmesenchymal transition(EMT)in stomach neopl
Objective Stomach neoplasms are the fourth most common malignancy and the second leading cause of cancer-related deaths worldwide,there are many factors that cause stomach neoplasm,and the pathogenesi
会议
stomach neoplasmNMIEMTNF-κ BHDACs
Mannose-mediated inhibitory effects of PA-MSHA on invasion and metastasis of hepatocellular carcinom
Objective The elevation of high mannose glycans is a common feature of malignant cells,and has been suggested to be the basis for alternative cancer therapy for several years.
会议
mannosemetastasisliver cacer
The lncRNA TP73-AS1 promotes ovarian cancer cell proliferation and metastasis via modulation of MMP2
Objective Ovarian cancer is one of the most common gynecologic malignancy with poor prognosis.Recently,long noncoding RNAs(lncRNAs)have been identified as key regulators in cancer development.
会议
long noncoding RNAMMP2MMP9ovarian cancerproliferationTP73-AS1
MiR-30e-5p impedes invasion and migration by targeting MTDH via angiogenesis in head and neck squamo
Objective Head and neck squamous cell carcinomas(HNSCC)is the worlds sixth-largest tumor that responsible for 650,000 cases annually over the past a few decades.While advanced medical technologies bee
会议
Head and neck squamous cell carcinomasmiR-30e-5pInvasionMigrationMTDHAngiog
Kir2.1-Notch2defines a more malignant subgroup in group3/4medulloblastoma
目的 Kir2.1 is one of malignant factors involved in Medulloblastoma(MB)progression,and a potential prognostic factor for the patients.This study aims to investigate the roles and molecular mechanisms of
会议
Kir2.1medulloblastomaNotch
NSDHL促进三阴性乳腺癌转移的机制研究
目的 肿瘤转移是导致乳腺癌患者死亡的主要原因。流行病学研究发现肥胖是乳腺癌患者预后不良的危险因素，而且代谢重编程是肿瘤的标志性特征之一。因此，本课题希望寻找在乳腺癌转移中发挥重要作用的脂质代谢基因，并探究其作用机制和临床意义。
会议
乳腺肿瘤NSDHL转移TGFβ
MicroRNA-488 inhibits motility and migration of tumor cells via down-regulating Fascin in breast can
Objective Breast cancer is the most common cancer in female worldwide,and metastasis is the leading cause of mortality in patients with breast cancer.It is urgent to clarify the underlying mechanisms
会议
microRNA-488Fascinbreast cancermotility
Id2调控结直肠癌细胞HCT116生长和侵袭转移的机制研究
目的 探讨Id2对人结直肠癌细胞生长和侵袭转移的影响及作用机制。方法 qRT-PCR 和Western Blot 检测六株人结直肠癌细胞中Id2 mRNA 和蛋白的表达。选取高表达Id2 的肠癌细胞株，感染慢病毒后用puromycin 筛选，构建稳定敲减Id2 的肠癌细胞株。
会议
Id2可能通过PI3K/AKT信号通路改变细胞周期蛋白EMT相关蛋白和MMPs/TIMPs的表达影响结直肠癌细胞的生长和侵袭转移
miR-302a reduces metastasis and cetuximab resistance in colorectal cancer by targeting NFIB and CD44
Objective Metastasis and drug resistance contribute substantially to poor prognosis of colorectal cancer(CRC)patients.miRNAs are essential regulators of CRC initiation and progression.
会议
Colorectal cancermiR-302ametastasiscetuximab resistance