目的 探讨CT引导下经皮微波消融术(MWA)联合TACE治疗原发性肝癌的疗效及预后.方法 自2009年5月至2012年12月,共对43例确诊肝癌患者行微波消融联合TACE治疗.患者肝内肿块1～3个,大小自4.5～13.0 cm,平均8.7 cm.初治时肝功能Child-Pugh A级31例、B级12例,白蛋白29.3～47.2 g/L,有3例患者合并少量腹水.治疗方法：43例患者均先行经皮TACE
目的：海蓝组织细胞增多症((sea blue histiocytosis,SBH)是一种伴血细胞增生活跃(骨髓增生异常综合症,骨髓增殖性疾病)血液疾病与先天性脂质代谢障碍的形态学表现.SBH以染色可见胞浆内大量海蓝色或海绿色颗粒得名.该病在临床上是一种罕见的常染色体隐性遗传疾病,以肝脾肿大,贫血,血小板减少为主要临床特点,可累及多脏器.本报道介绍了两例继发性海蓝细胞增多症的病例,旨在通过对临床表现
Aim: To explore an optimal treatment for HBeAg positive chronic hepatitis B(CHB)with high HBV load.Methods: One hundred and seventy-one suitable CHB patients were divided into three groups: Group A(n=
目的：非酒精性脂肪性肝病(NAFLD)，是指除外大量饮酒和其他明确的损害肝脏的因素所致的以弥漫性肝细胞脂肪变为病理特征的临床综合征，近年来发病率逐年升高，成为世界性健康问题.SENP3是翻译后修饰SUMO化的特异蛋白酶，影响蛋白质功能，且对细胞应激敏感，然而，在NAFLD发病过程中脂质代谢、氧化应激、细胞因子异常释放等都是对正常肝细胞的应激.该研究的目的是探讨SENP3在NAFLD发病过程中的变化
目的：延伸因子结合蛋白2(EFTUD2)具有pre-mRNA剪切、且能调控机体固有免疫的功能，本研究拟证实EFTUD2对乙型肝炎病毒(HBV)细胞内复制的抑制作用，并探讨EFTUD2的抗病毒能力是否与视黄酸诱导基因蛋白I(RIG-I)-IRF3信号通路的相关。
Aim: To compare the prognosis between the patients with progression into acute-on-chronic liver failure(ACLF)from acute deterioration of preexisting chronic liver disease and patients without this pro
aims Ultrasound microbubbles are now being used as carriers of drugs or genes in targeted treatment of carcinoma.The purpose of the study was to investigate the effect of lipid microbubbles loaded doc
Object:Interferon-α(IFN-α)treatment induce antiviral responses by induction of interferon stimulated genes,which can directly inhibit viral replication,as well as influence innate and adaptive immune
(-)-Epigallocatechin-3-gallate(EGCG),a major polyphenol component of green tea,has recently been identified as an inhibitor of hepatitis C virus(HCV)entry.Here,we examined whether EGCG can enhance hep
Objective: To investigate the risk factors of antibiotic prophylaxis failure in decompensated cirrhosis patients with upper gastrointestinal bleeding.Methods:Eighty-two cirrhosis patients with upper g