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目的 比较新型眼生物测量仪Tomey OA-2000与IOLMaster获得的白内障患者眼生物参数的差异性和一致性。方法 前瞻性研究。纳入白内障术前检查者74例（74眼），分别应用Tomey OA-2000和IOLMaster进行测量，获得眼轴长度（axial length，AL）、角膜曲率（keratometry，K）、前房深度（anterior chamber depth，ACD）和角膜横径（white to white，WTW）等参数。配对t检验分析两种设备获得的眼生物参数之间的差异。Bland-Altman散点图分析两种设备获得的各生物参数之间的一致性。结果 Tomey OA-2000获得的AL、平坦K（flat K，Kf）值、陡峭K（steep K，Ks）值、平均K（mean K，Km）值、中央角膜厚度（central corneal thickness，CCT）、ACD、晶状体厚度（lens thickness，LT）、瞳孔直径（pupil diameter，PD）和WTW值分别为（24.26±2.71）mm、（44.09±1.76）D、（45.01±1.73）D、（44.55±1.72）D、（518.41±34.18）μm、（3.07±0.48）mm、（4.48±0.61）mm、（4.07±0.95）mm和（11.50±0.52）mm。IOLMaster获得的AL、Kf、Ks、Km、ACD和WTW值分别为（24.33±2.69）mm、（44.21±1.74）mm、（45.15±1.76）D、（44.69±1.74）D、（3.04±0.46）mm和（11.65±0.41）mm。Tomey OA-2000和IOLMaster获得的AL、Kf、Ks、Km、ACD和WTW差值分别为（-0.07±0.10）mm（t=-5.99，P<0.01）、（-0.12±0.21）D（t=-4.14，P<0.01）、（-0.14±0.20）D（t=-5.88，P<0.01）、（-0.12±0.13）D（t=-7.44，P<0.01）、（0.03±0.14）mm（t=1.99，P=0.05）和（-0.14±0.32）mm（t=-3.73，P<0.01）。两种设备获得的AL、Kf、Ks、Km、ACD的95％一致性界限（LoA）其上下限最大绝对值分别为0.27 mm、0.50 D、0.53 D、0.38 D、0.30 mm，一致性较好；而WTW的95% LoA为0.78 mm，一致性较差。结论 Tomey OA-2000和IOLMaster获得的AL、K、ACD差异小，一致性好。
Objective To compare the differences and consistency of ocular biological parameters of cataract patients obtained with the new ophthalmic biometrics Tomey OA-2000 and IOLMaster. Methods Prospective study. Totally 74 patients (74 eyes) with preoperative cataract were included in this study. Tomey OA-2000 and IOLMaster were used respectively to measure axial length (AL), keratometry (K), anterior chamber depth , ACD), and white to white (WTW) parameters. Paired t-test analyzes the differences in ocular biological parameters obtained by both devices. The Bland-Altman scattergram analyzes the agreement between the biological parameters obtained by both devices. Results AL, flat K (Kf), steep K (Ks), mean K (Km), central corneal thickness (CCT) The values of ACD, lens thickness (LT), pupil diameter (PD) and WTW were (24.26 ± 2.71) mm, (44.09 ± 1.76) D, (45.01 ± 1.73) D and (44.55 ± 1.72) D, (518.41 ± 34.18) μm, (3.07 ± 0.48) mm, (4.48 ± 0.61) mm, (4.07 ± 0.95) mm and (11.50 ± 0.52) mm respectively. The values of AL, Kf, Ks, Km, ACD and WTW were (24.33 ± 2.69) mm, (44.21 ± 1.74) mm, (45.15 ± 1.76) D, (44.69 ± 1.74) D and (3.04 ± 0.46) mm and (11.65 ± 0.41) mm. The differences of AL, Kf, Ks, Km, ACD and WTW obtained by Tomey OA-2000 and IOLMaster were -0.07 ± 0.10 mm (t = -5.99, P <0.01) and (-0.12 ± 0.21) D = -4.14, P <0.01), (-0.14 ± 0.20) D (t = -5.88, P <0.01), (-0.12 ± 0.13) D (t = -7.44, P <0.01), (0.03 ± 0.14) mm (t = 1.99, P = 0.05) and (-0.14 ± 0.32) mm (t = -3.73, P & lt; 0.01). The 95% agreement limits (LoA) of the AL, Kf, Ks, Km and ACD obtained by the two devices are 0.27 mm, 0.50 D, 0.53 D, 0.38 D and 0.30 mm, respectively, ; While WTW’s 95% LoA was 0.78 mm, with less concordance. Conclusion The difference of AL, K and ACD between Tomey OA-2000 and IOLMaster is small and consistent.