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对２４ 例恶性肿瘤患者应用自体异构化瘤苗治疗，并与相应对照组比较，通过治疗前后外周血Ｔ 淋巴细胞亚群ＣＤ３ ＋ 、ＣＤ４ ＋ 、 ＣＤ８ ＋ 、 ＣＤ４ ＋ ／ ＣＤ８ ＋ 及ＮＫ 细胞活性的检测， 观察患者细胞免疫功能的变化情况。结果，研究组治疗后ＣＤ３ ＋ 、ＣＤ４ ＋ 、ＣＤ４ ＋ ／ＣＤ８ ＋ 比值和ＮＫＣ 活性都比治疗前显著增加（ Ｐ＜ ０ ．０１） ，而对照组无明显变化（ Ｐ＞ ０ ．０５） 。提示异构化瘤苗能有效地帮助恶性肿瘤病人重建受损的Ｔ 淋巴细胞网络，恢复细胞免疫功能，达到治疗和预防肿瘤转移与复发的目的。
24 patients with malignant tumors were treated with auto-isomerized tumor vaccines and compared with the corresponding control group. Peripheral blood T lymphocyte subsets CD3 +, CD4 +, CD8 +, CD4 + / CD8 + and NK cell activity before and after treatment The detection of the patient’s cellular immune function changes. As a result, the ratios of CD3 +, CD4 +, CD4 + /CD8 + and NKC activity in the study group were significantly higher than those before treatment (P < 0.01), while there was no significant change in the control group (P> 0.05). It is suggested that the isomerized tumor vaccine can effectively help the malignant tumor patient to rebuild the damaged T lymphocyte network, restore cellular immune function, and achieve the purpose of treating and preventing tumor metastasis and recurrence.