【摘 要】
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Objective To compare the difference of apparent diffusion coefficient (ADC) on the squamous cell carcinoma (SCC) and on tumor boundary of the tongue; To evaluate the value of diffusion-weighted MRI (M
【机 构】
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上海交通大学医学院附属第九人民医院
【出 处】
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中华放射学学术大会2016、中华医学会第23次全国放射学学术大会暨中华医学会第24次全国影像技术学术大会
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Objective To compare the difference of apparent diffusion coefficient (ADC) on the squamous cell carcinoma (SCC) and on tumor boundary of the tongue; To evaluate the value of diffusion-weighted MRI (MR-DWI) in the research of tumor boundary associated with the tongue SCC. Methods 35 cases of tongue SCC were determined pathologically and examined with MR-DWI prior to the operation. With a bvalue of 100s/mm2, the average ADC was calculated for each SCC lesion and on 5 mm and 10 mm boundary of the tumor. The results were divided into two groups: group A with a higher ADC on the lesion than on the tumor boundary and group B the opposite. Retrospective analysis showed statistically significant difference (P<0.05) in the average ADC on the lesion compared to the tumor boundary. Results(1) With a b-value of 1000 s/mm2, the ADC on the lesion was significantly different (P> 0.05) to the tumor boundary, while no significant difference was shown between the 5 mm and 10 mm boundaries. (2) Between group A and group B, the ADC was not significantly different in the central and peripheral regions of the SCC and on the 5 mm and 10 mm boundaries. (3) Among the 35 cases, SCC lesions at the tongue body (28 cases) and at the tongue root (7 cases) showed significantly different ADC than that of the 5 mm and 10 mm tumor boundaries, while no significant difference was shown between the tongue and the tongue root or between the 5 mm and 10 mm boundaries. (4) SCC lesions of pathological gradeⅠ (4 cases), Ⅱ (28 cases) and Ⅲ (3 cases) showed no significant difference in the average ADC to that of the 5 mm and 10mm tumor boundaries. Conclusion MR-DWI has a clinical value in determining the tumor boundary of the tongue SCC.
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