@@ Conventional enterocystoplasty is always associated with a variety of complications，which in turnstimulated the development of altemative methods for bladder augmentation.The need to find an altemative to the use of bowel for urinary reconstruction has renewed research interests involving bladderregeneration.Small-intestinal submucosa (SIS) is an acellular，nonimmunogenic，biodegradable，xenogeneic，collagen-based material that iS derived from the submucosa layer of porcme smallintestine.