论文部分内容阅读
Protein kinase monopolar spindle 1 plays an important role in spindle assembly checkpoint at the onset of mitosis [1].
Identification of the hot spot residues for ATP substrate and the pyridine derivative inhibitor CCT2
【摘 要】
：
Protein kinase monopolar spindle 1 plays an important role in spindle assembly checkpoint at the onset of mitosis [1].
【作 者】
：
【机 构】
：
Collaborative Innovation Center of Chemistry for Life Sciences,Institute of Immunology and the CAS K
【出 处】
：
中国化学会第十届全国化学生物学学术会议
【发表日期】
：
2017年10期
其他文献
Design,synthesis and anticancer activity of 1,8-naphthalimide-uridine conjugates by targeting telome
G-quadruplex is formed in specific G-rich sequences such as telomere 3-overhang and the promoter of oncogenes.
Design,synthesis and interaction of 4,5-diazafluorene derivatives bearing 1,3-disubstituted pyrazole
Fifteen novel 4,5-diazafluorene derivatives bearing a 1,3-disubstituted pyrazol moiety were designed,synthesized,evaluated for their antitumor activity at cellular level by CCK-8,wound healing and FCM
Structure-based design,synthesis,insecticidal activityevaluation of novel bicyclic pyrazole carboxam
Molting hormone is a kind of insect growth regulators which Belonging to one of an insect growth regulator.Ecdysone receptor(EcR/USP)only existed in insect and it can bind to the molting hormone to ef
A novel environmental responsive peptide hydrogel,which exhibits response to pH and redox,was presented.
Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5(TLR5)/Flagellin Complex Inhibitors
Protein-protein interactions have been regarded as "undruggable"despite their imporatance in many biological processes.
One of the major limiting factors in Natural products drug discovery is that pharmaceutical companies have been traditionally designed to target individual factors in a disease system,but diseases are
会议
Natural Products from Chinese Herbal Medicine for Drug Discovery:Proteome-wide Mapping of Interactom
Traditional Chinese Medicine(TCM,Zhong-Yi)has existed for thousands of years.A key component of TCM is Chinese Herbal Medicine(CHM,Zhong-Yao,or Zhong-Caoyao),which provides pharmacologically active co
Combination of virtual screening protocol by in silico towards the discovery of novel HPPD inhibitor
4-Hydroxyphenylpyruvate dioxygenase(EC 1.13.11.27,HPPD)is a potent new bleaching herbicide target.
Melanin has the significant physiological function not only in the growth of insect but also in fungi and bacteria.
Glycosylation of CD147 promote cancer cell invasion:regulation study with novel inhibitors and DNA-e
Tumor migration is one of the most important reasons for failure treatment of patients in late-stage [1].