PURPOSE To investigate the clinical phenotypes for Leber congenital amaurosis (LCA) and early-onset severe retinal dystrophy (ESRD) associated with RPE65.
Purpose To identify pathogenic mutations responsible for Usher syndrome (USH) in five unrelated Chinese USH families.Methods Clinical data and genomic DNA were collected for patients with USH and avai
Background Glaucoma is a group of disorders with optic neuropathy.It is characterized by progressive injury to retinal ganglion cells and their axons and causes progressive visual field loss.Glaucoma
Purpose To estimate and compare change in iris crosssectional area (IA) and iris volume (IV) after physiologic and pharmacologic mydriasis in subjects with different mechanisms for primary angle closu
Purpose Viral infection of the cornea can result in inflammation and scarring and eventually lead to blindness.Polyinosinic-polycytidylic acid [poly(l:C)], an analog of viral double-stranded RNA, indu
Objective To investigate the relationship of vision-related quality of life (VRQOL) and visual function in patients undergoing pars plana vitrectomy(PPV) combined with internal limiting membrane(ILM)
PURPOSE: To report a patient presenting with necrotizing scleritis, peripheral ulcerative keratitis and optic neuritis ,in the meanwhile, the patient is associated with both rheumatoid arthritis and s
Objective An analysis method based on the corneal dynamic deformation video recorded by corneal visualization Scheimpflug technology (Corvis ST) was developed to analysis and determine several new int
Purpose Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4) play a crucial role in the primary defense against fungal pathogens, and since genetic variation in genes may regulate the response.
目的 探讨眼球经眶入颅后的手术复位治疗方案.XX,男,32岁,因"钢管插入右眼眶后疼痛、流血6小时"于2014年5月14日急诊到我科就诊.查体:右眼下睑可见弧形皮肤裂伤长约5cm.拉钩拉开右眼眼睑,上睑结膜近内眦处及下睑结膜内1/2处撕裂,未见眼球,眶内组织紊乱不清.CT提示:右眼球部分脱入颅内,右侧眼眶及颅底多发骨折,鼻窦积血,右眼视神经及眼外肌结构不清.