【摘 要】
：
[目的]探讨射波刀治疗鼻咽癌颅底复发和转移病灶的毒性与疗效.[方法]回顾性分析2006.10～2014.3射波刀治疗鼻咽癌调强放疗后颅底复发或转移的患者21例.射波刀治疗采用颅骨追踪方式,67％～83％剂量线,给予2400～5000cGy剂量,4～10次分割完成.通过影像学和症状随访进行毒性和疗效的评估.采用Kaplan-Meier方法进行局控疗效和总生存评估.[结果]1、2、3年局部无进展生存率
论文部分内容阅读
[目的]探讨射波刀治疗鼻咽癌颅底复发和转移病灶的毒性与疗效.[方法]回顾性分析2006.10～2014.3射波刀治疗鼻咽癌调强放疗后颅底复发或转移的患者21例.射波刀治疗采用颅骨追踪方式,67％～83％剂量线,给予2400～5000cGy剂量,4～10次分割完成.通过影像学和症状随访进行毒性和疗效的评估.采用Kaplan-Meier方法进行局控疗效和总生存评估.[结果]1、2、3年局部无进展生存率均为80.2％,1、2、3年总生存分别为：67.7％、45.1％、30.1％.患者对射波刀治疗耐受良好,主要毒副反应有：面部麻木疼痛(4例,19％),放射性口腔炎(2例,9.5％),头晕头痛(2例,9.5％),对症治疗后均好转.鼻腔难控性出血2例(9.5％).在随访期内,7例(33.3％)存活,病灶通过射波刀治疗后都得到了控制.12例(57.1％)死亡,2例(9.5％)失访.[结论]采用射波刀治疗鼻咽癌颅底复发或转移局控疗效显著,毒副作用小.
其他文献
Background:to establish a simple and convenient prognostic score based on clinical routine factors to stratify nasopharyngeal carcinoma(NPC) patients with bone metastasis(BM) into risk groups with dif
Purpose:This study was to investigated whether BRCC3 can be a prognostic marker for nasopharyngeal carcinoma and its possible radiation sensitivity related-regulating mechanism.
Purpose:The aim of this study was to investigate the status and dose relationship of hypothyroidism(HT)induced by intensity-modulated radiotherapy(IMRT) for patients with nasopharyngeal carcinoma (NPC
Background and Purpose:The prognostic value of comorbidity nasopharyngeal carcinoma is poorly characterised,and further investigation is warranted due to its specific biological behavior and epidemiol
Background:To evaluate the treatment outcomes and toxicities of intensity-modulated radiation therapy (IMRT), for children and adolescents with locoregionally advanced nasopharyngeal carcinoma(NPC).Me
Purpose:To compare the Chinese 2008 and the 7th edition the American Joint Committee on Cancer / Union International Cancer control(AJCC / UICC) staging systems for nasopharyngeal carcinoma,and provid
Background and Purpose:The aim of this study was to propose new suggestions of staging system for nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiation therapy(IMRT).Materials and
[目的]头颈部淋巴结的影像学分区越来越受到国际放疗界的关注.2013年，几个大型的肿瘤中心达成协议，在以往的基础上提出了更新版的淋巴结分区.但基于该分区的鼻咽癌淋巴结转移规律尚无相关报道.本研究的目的是总结初治鼻咽癌的淋巴结转移分布规律，为调强放射治疗(IMRT)提供颈部照射范围的依据.[材料与方法]回顾性分析2010年至2013年期间我院治疗的鼻咽癌患者的MRI资料，由鼻咽癌多学科讨论组阅片，详
[目的]探讨70岁以上老年鼻咽癌患者治疗后临床疗效,并分析其预后因素.[方法]回顾性分析我院于2008年1月至2013年12月初治鼻咽癌170例,年龄70～82岁,中位年龄76岁,男131例,女39例,T分期T1、T2、T3、T4分别为20例、20例、71例和59例,而N分期N0、N1、N2、N3分别为26例、62例、61例和21例,接受序贯化疗120例,而放疗采用适形或调强放疗146例,常规放疗
Background:Both nasopharyngeal carcinoma (NPC) and hepatitis B virus (HBV) infection are prevalent in southern China.Recently, HBV-infected patients with diffuse large B-cell lymphoma or multiple myel