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  5. miR-125a mediates the effects of Notch signaling on promoting myeloid survival and M1 macrophage pol

miR-125a mediates the effects of Notch signaling on promoting myeloid survival and M1 macrophage pol

来源 :2015亚太发育生物学国际研讨会 | 被引量 : 0次 | 上传用户：dyq135621
【摘 要】
：
Macrophages play a critical role in host defense and homeostasis maintenance.Our previous work and the other literatures showed Notch signal is essential for M1
【作 者】
：
Jun-Long Zhao Fei Huang Fei He Chun-Chen Gao Shi-Qian Liang Peng-Fei Ma Hua Han Hong-Yan Qin 
【机 构】
：
StateKeyLaboratoryofCancerBiology,DepartmentofMedicalGeneticsandDevelopmentalBiologyDepartmentofHepa
【出 处】
：
2015亚太发育生物学国际研讨会
【发表日期】
：
2015年9期
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Macrophages play a critical role in host defense and homeostasis maintenance.Our previous work and the other literatures showed Notch signal is essential for M1 macrophage polarization in inflammatory stimulation, but the mechanisms by which Notch-mediated macrophage polarization has been unclear.In our study, we identify miR-125a as a new downstream molecule of the Notch pathway through microRNA array.
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