【摘 要】
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The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is characterized by a high fever and a high mortality in pigs of all ages and has severely affected the pork indust
【机 构】
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Institute of Special Wild Economic Animal and Plant Science, CAAS
【出 处】
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2013国际猪繁殖与呼吸综合征学术研讨会
论文部分内容阅读
The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is characterized by a high fever and a high mortality in pigs of all ages and has severely affected the pork industry of China in the last few years.An attenuated HP-PRRSV strain,TJM,was obtained by passaging the HP-PRRSV TJ strain on MARC-145 cells for 92 passages.Porcine reproductive and respiratory syndrome virus (PRRSV) and antibody-free pigs were inoculated intramuscularly with TJM (105.0 TCID50) and challenged on 28,60,120,and 180 days post immunization (DPI).Results showed that 5/5,5/5,5/5,and 4/5 immunized pigs were protected from the lethal challenge and did not develop fever and clinical diseases at each challenge,respectively.
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