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Objective: To measure upper airway CT morphology of healthy Chinese and identify the lower limit for judging narrow sites in OSAHS patients.Setting: Shanghai Jiao Tong University Affiliated Sixth People's Hospital.Methods: 420 volunteers were recruited and 300 healthy adults who fit the inclusion criteria participated in the study.A standard CT scan procedure was carried out in all participants while quiet breathing.Through obtained images, upper airway was separated into four regions: nasopharyngeal region (NP), retropalate region (RP), retroglossal region (RG), hypopharynx region (HP).Six targeted levels were measured to represent the morphology in each region (four fixed level from each region and narrowest level of retroglossal region/retropalate region).Primary measurement was the cross sectional area.Lower limit of cross section area in each level of upper airway were calculated.Results: Upper airways of men are significantly larger than women, while no difference was found between different age groups.The lower limits of upper airway for healthy men are: 251.3mm2 in NP, 54.6mm2/124.6mm2 in narrowest/fixed level of RP, 121.2mm2/138.2mm2 in narrowest/fixed level of RG and 137.3mm2 in HP.For healthy women, the corresponding values are: 230.8mm2, 54.1mm2/96.9mm2, 100.9mm2/112.8mm2 and 108.8mm2.Conclusion: The reference values of upper airway in healthy Chinese adults were established.Upper airways smaller than corresponding lower limit may be considered existence of narrow sites.