AIM:Long non-coding RNAs (lncRNAs) are transcripts with length greater than 200 nucleotides and without protein-coding function.They are emerging as new regulators in cancer biology by acting as turnor suppressors or oncogenes.They may even be employed as biomarkers for cancer diagnosis and prognostication.However, the global expression patterns and functional roles of lncRNAs in the majority of cancer types,including glioma, remain largely unknown.Gliomas are the most common primary brain tumors in adults.