KPNA2基因的过表达对上尿路移行细胞癌预后的影响

来源 :2013年广东省医学会泌尿外科学学术年会 | 被引量 : 0次 | 上传用户：tang355402

【摘要】

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目的:观察核转运蛋白α2 (karyopherin alpha 2,KPNA2)基因在上尿路移行细胞癌中的表达及其对肿瘤细胞系增殖及凋亡的影响,探讨其做为预测上尿路移行细胞癌膀胱复发及预后的肿瘤标志物.方法:1,应用组织芯片和免疫组化技术观察KPNA2基因在218例上尿路移行细胞癌中的表达情况.2,在尿路移行上皮癌细胞系中过表达和敲低KPNA2基因,应用CCK-8、流式细胞术等检测其对肿瘤细胞增殖

【作者】

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史本涛李学松周利群苏博兴李贤新杨尚琪

【机构】

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北京大学深圳医院泌尿外科北京大学第一医院泌尿外科

【出处】

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2013年广东省医学会泌尿外科学学术年会

【发表日期】

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2013年12期

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KPNA2基因的过表达对上尿路移行细胞癌预后的影响

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