The scientific literature indicating that oxidative stressis unhealthy and leads to serious disease is compelling.Increased oxidative stress generally describes a condition in which cellular antioxidant defenses are inadequate to completely inaetivate the reactive oxygen species (ROS) and reactive nitrogen species (RNS).This can occur because of excessive production of ROS/RNS and/or loss of antioxidant defenses.The major consequences of oxidative stress are damage to DNA/RNAs, lipids, and proteins, which can severely compromise cell health and viability, ultimately leading to the development of multiple acute and chronic human diseases, such as cancer, heart disease, diabetes, and neuro-degeneration, as well as with the aging process itself.