Herbal Medicinal Product on the Basis of Chelidonium Majus L.NSC-631570

来源 :2005 WHTS'3rd Annual Congress of International Drug Disc | 被引量 : 0次 | 上传用户:hongshu16
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  Chelidonium majus L.(greater celandine) is the only species of the tribe Chelidonieae of the Papaveraceae family.Chelidonine is the main alkaloid of greater celandine roots and makes up 80% of the total alkaloid content.Major alkaloids are: chelidonine, protopine, allocryptopine, chelerythrine, sanguinarine.They make up 60-80% of the total alkaloid content of the raw plant.The plant is for hundreds years well known due to its multiply biological activity, including anticancer, antiviral, antimicrobial effects.However, water-insolubility makes clinical administration of the constituents of the drug and its extract possible only in form of local or peroral administration.Alkaloids were made water soluble by a patented process.Starting material is greater celandine roots.The alkaloids are extracted from the dried drug and then purified.
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