The purpose of the paper is to develop a novel simulation system for ship propulsion plant. The nonlinear mathematical model of main propulsion system of a large container ship is established, consisting of the large low speed two-stroke diesel engine, shaft, fixed pitch propeller and ship hull dynamics. What’s more, a new full mission ship diesel main propulsion plant remote simulation system, including the bridge, ECR and local control function, is developed by utilizing practical devices of CAN bus and touch screen, as well as the view classes switching and database management techniques. The navigation condition of the main propulsion of the ship can be properly simulated and satisfactory visualization is gained by the system. Therefore, it can be adopted not only as a favorable platform of intelligent control algorithm for marine main diesel propulsion plant, but also as one critical part of the crew training facilities under laboratory condition.