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5. Integrative approach to cancer driver gene discovery from somatic mutations

Integrative approach to cancer driver gene discovery from somatic mutations

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：cwsyydr01

【摘 要】

：

Knowledge of driver genes whose mutations lead to tumor-genesis is important for understanding the mechanisms of cancer and for identifying promising drug targets.

【作 者】

：

Xin He Siming Zhao Matthew Stephens 

【机 构】

：

Department of Human Genetics,University of Chicago,IL,60637,USA

【出 处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

Cancer Somatic mutations Driver genes Mixed model 

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　　Knowledge of driver genes whose mutations lead to tumor-genesis is important for understanding the mechanisms of cancer and for identifying promising drug targets.

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